Features of the simultaneous course of pulmonary aspergillosis and tuberculosis on the background of type 1 diabetes mellitus (clinical case)

Aim. To analyze the features of simultaneous course pulmonary aspergillosis and multidrug-resistant tuberculosis (MDR-TB) on background type 1 diabetes mellitus, example a clinical case our practice. Materials methods. Clinical practice MDR-TB mellitus in patient, who was treated Pulmonary department No. 2 base Phthisiatry Pulmonology Department Zaporizhzhia State Medical University at Communal Non-Commercial Enterprise “Zaporizhzhia Regional Diagnostic Center Pulmonology” Council. Results. In presented case, patient had been suffering from for 8 years receiving insulin therapy all these years. One year before TB disease, he contact with an index but categorically refused preventive chemotherapy. Also, did not make comparison X-ray TCO after 6 months, as person. aspergilloma left lung were diagnosed simultaneously severe condition decompensated form intoxication syndrome inflammatory process, massive hemoptysis. Aspergilloma using cultural examination bronchial aspirate Aspergillus, which difficult to diagnose. Diagnosis also difficult, because MBT, contributed timely correct appointment antimycobacterial therapy. Surgery contraindicated, decompensation. Persistent hyperglycemia remained, despite fact antifungal constant correction prescribed patient. Endocarditis quickly developed reason patient’s death. Conclusions. The caused persistent hyperglycemia, immune disorders this made body susceptible bacterial fungal (aspergillosis) infections, led development complication endocarditis A big mistake his categorical refusal by receive chemotherapy, person view this, presence diabetes, should have neglected it. And result, MDR-TB, one after. At same time, TCO, person, possible missing early diagnosis aspergilloma. That’s why, treatment radiological thoracic cavity organs are especially important, is most common premorbid aspergillosis.